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Watch our step-by-step video guide

SOLIQUA 100/33 is administered using the prefilled SoloStar® pen.

Watch our video below to help you learn the 6 steps for taking SOLIQUA 100/33. You can also read our illustrated instructions.

Please be sure to view each of the chapters in the video below. Click the list icon in the lower right-hand corner of the video player to view all chapters.

Before you use SOLIQUA 100/33

SOLIQUA 100/33 is administered using the prefilled SoloStar® pen. Your healthcare provider should teach you how to inject SOLIQUA 100/33.

However, before you use your pen:
  • Read all the instructions that came with your SOLIQUA 100/33 pen.
  • Talk to your healthcare provider if you have questions or do not understand the instructions.

If you do not follow the instructions correctly, you may get too much or too little medicine.

Get to know your pen

The SOLIQUA 100/33 pen uses a small thin needle that goes just under the skin and features a dose selector dial and push-button injection to help you select and inject your prescribed dose. There is also a large dose window so you can see your selected dose. Each line in the dose window equals 1 unit of SOLIQUA 100/33.

When dialing your dose:
  • Do not dial your dose by counting the clicks or you may dial the wrong dose.
  • Always check the number in the dose window to make sure you have dialed the correct dose.
  • As you dial your dose, you may notice that the dose window is black between 2 units and 15 units. This is because SOLIQUA 100/33 should not be used for a dose of less than 15 units. Continue dialing until you reach the number for your prescribed dose. Do not use the pen if your single daily dose is less than 15 units (the dose window will be black).
Important to know:
  • If you have problems handling the pen or can’t see the numbers in the dose window clearly, have another person inject your dose.
  • Do not share your SOLIQUA 100/33 pen with other people, even if the needle has been changed.

SOLIQUA 100/33 (insulin glargine & lixisenatide injection) 100 Units/mL & 33 mcg/mL Pen

Needle not included with pen. Always use needles compatible with your pen.

If you do not know which needles to use, ask your healthcare provider or pharmacist.

When to inject

  • You should inject your dose within one hour before your first meal of the day, preferably at the same time each day.
  • If you miss a dose, skip the dose and continue as prescribed on the next day. You should never administer two doses on the same day or increase the dose to make up a missed dose.

Choosing a place to inject

You can inject SOLIQUA 100/33 in one of three areas of your body:

  • Anywhere in your stomach area, except for a two-inch radius around your navel
  • In the fatty tissue on the outer back area of your upper arm
  • In your thighs, away from your knee

Always rotate injection sites within the area you have selected. DO NOT use the same exact spot for each injection. Do not re-use needles or use a syringe to remove medicine from your pen.

Choosing an injection site for SOLIQUA 100/33

Storing your SOLIQUA 100/33 pen

Before first use:
  • Store with cap on in original packaging.
  • Refrigerate between 36°F and 46°F (2°C and 8°C).
  • Do not freeze. If you accidentally freeze your pen, throw it away.
  • Discard if past expiration date and use a new pen.
After first use:
  • Do not put the pen back in the refrigerator.
  • Keep your pen at room temperature below 86°F (30°C).
  • Do not store your pen with needle attached.
  • Store with cap on to protect from light.
  • Discard the pen 14 days after first use.

Always keep your pen and all medicines out of the sight and reach of children.

How to use
SOLIQUA 100/33


View illustrated step-by-step instructions you can download, print, and take anywhere.

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