Whether you’re new to an injectable medicine or are already familiar with SoloStar® or other injection pens, it’s important to know how to use your SOLIQUA 100/33 SoloStar® pen. Learn about its features and review helpful tips below.

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SOLIQUA 100/33 is injected once a day within one hour before your first meal using the prefilled disposable SoloStar® injection pen, the most widely used pen in the United States.


The SOLIQUA 100/33 pen

For a daily dose range of 15-60 units. Each pen contains 300 units of medicine.

Special features help you select and inject your prescribed dose


Small thin needle that goes just under the skin.

Needle not included with pen. Always use needles compatible with your pen.


Dose selector dial and push-button injection work together so you can select and inject your prescribed dose.


Large dose window lets you clearly see your selected dose. Each line in the dose window equals 1 unit of SOLIQUA 100/33.

When dialing your dose

  • Do not dial your dose by counting the clicks or you may dial the wrong dose.
  • Always check the number in the dose window to make sure you dial the correct dose.
  • As you dial your dose, you may notice that the dose window is black between 2 units and 15 units. This is because SOLIQUA 100/33 should not be used for a dose of less than 15 units.

Helpful tips for using SOLIQUA 100/33

Before you use SOLIQUA 100/33

Your healthcare provider should teach you how to inject SOLIQUA 100/33. However, before you use your pen:

  • Read all the information that came with your pen, including the Instructions for Use.
  • Speak with your doctor or healthcare provider if you have questions about your pen or do not understand the instructions.
  • Know your dose and don’t change your dose unless directed by your doctor.

Take special note

  • Do not re-use needles.
  • Do not use a syringe to remove medicine from your pen.
  • Do not share your pen with other people, even if the needle has been changed.
  • Check the label on the SOLIQUA 100/33 pen each time you inject to make sure you are using the correct medicine.
  • If you have problems handling the pen or can’t see the numbers in the dose window clearly, have another person prepare and inject your dose.
  • Finding the right dose can take some time. Stay in close contact with your doctor about how you feel so he or she can adjust your dose to find the dose that works best for you.

Storing your SOLIQUA 100/33 pen

Before you use your pen for the first time:

  • Store with cap on in original packaging.
  • Refrigerate between 36°F and 46°F (2°C and 8°C).
  • Do not freeze. If you accidentally freeze your pen, throw it away.
  • Discard if past the expiration date and use a new pen.

After you use your pen

  • Do not put the pen back in the refrigerator.
  • Keep your pen at room temperature below 77°F (25°C).
  • Do not store your pen with the needle attached.
  • Store with cap on to protect from light.
  • Discard the pen 28 days after first use.

Always keep your pen and all medicines out of the sight and reach of children.

Making the change to SOLIQUA 100/33?

It’s natural to have questions when learning how to inject a new medicine for the first time. Watch our step-by-step video to help you get started.